IDEA

IT COULD BE OURS OR IT MIGHT BE YOURS - WE'LL DEVELOP IT TOGETHER...

LABORATORY

TO REALISE THE IDEA - COMINNEX CHEMISTS START TO DESIGN AND SYNTHESIZE...

HANDLING

WHEREVER YOU ARE - WE WILL SHIP QUICKLY, RELIABLY, GLOBALLY!

Technology Enabled Libraries

With decades of experience behind us, our team is brimming with novel chemistry ideas, whilst our design philosophy centers on totally novel yet fully lead-like libraries…

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DEL Building Blocks

ComInnex is the leading provider of building blocks for DNA-encoded libraries. Our research in this area is managed in an industry pioneering Open Innovative collaboration…

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Custom Chemistry Services

When internal capacity is tight then is time to call in the experts! Our team of highly skilled chemists has expertise in complex  performed synthetic sequences (up to 15 steps)

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Research & Development

Passionate about chemistry our team is continuously looking for new and better ways to synthesize compounds and generate novel libraries…

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Fostering Communities to Advance Science Through Sharing And Learning

Alex Drijver

Chief Executive Officer, ComInnex Inc.

SHARING & COMMUNITY

 We connect scientists in this rapidly evolving area, providing an effective collaborative platform for sharing and education, thriving on a common understanding for technical requirements, right down to the basic building block level…

EDUCATION & LEARNING

 Using this extensive knowledge as the basis to drive chemistry developments in pursuit of excellence….

ADVANCE & PROGRESS SCIENCE

 We are proud to have several leading global pharmaceutical organizations, and prominent biotech service providers working with us on this exciting field, supporting scientific progress and advancement of research…
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Custom Chemistry solutions

ComInnex’s staff has served its partners for over 12 years synthesizing novel or known marker compounds or other organic molecules. The current infrastructure enables our scientists to prepare final targets from mg to 50g scale in purity up to 98%.

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Diverse Libraries

Our design philosophy centers on high quality lead-like libraries rather than “combinatorial-like” ones. Our screening sets are typically 100 – 300 members per library in order to sample chemical space effectively and provide medicinal chemists with excellent starting points for further optimization.

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Focused & Targeted Libraries

Over the last 10 years ComInnex’s team has accumulated industry leading experience in both design and synthesis of focused libraries. Focused libraries are typically designed at ComInnex to assist our partner’s early lead follow-up efforts.

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Building Blocks for DNA Encoded Libraries

Affinity selection-based screening of large DNA-encoded libraries of lead-like molecules is now a validated method to identify bioactive compounds and it represents the best avenue to interrogate protein targets with the full diversity of available chemicals.

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Medicinal Chemistry Services

Hit and lead optimizations require extensive and meaningful expertise in the art. ComInnex’s medicinal chemistry leadership has developed 7 preclinical candidates that have entered the preclinical development phase. With this background we are confident that our team will take our partner’s optimization projects as far as possible and we can develop new or follow-on lead series if required.

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Fragment Design and Synthesis

For several years ComInnex has been providing its partners with a range of exclusive and custom made fragments, meaning that our partners can access technology enabled sets of molecules synthesized either from ComInnex intermediates or commercial starting materials. Using our suite of technologies, we can also transform our partners’ intermediates to novel fragments in order to further enhance the proprietary nature of the new compounds to be synthesized.

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ComInnex facilitates and provides collaborative working group environments. Find out how we can help you advance your scientific research…