Libraries

With decades of experience behind us, our team is brimming with novel chemistry ideas, whilst our design philosophy centers on totally novel yet fully lead-like libraries.

Our bespoke screening sets are typically have 100 – 300 members per library in order to sample chemical space effectively and provide medicinal chemists with excellent starting points for further optimization. We use a range of technologies like flow and photochemistry next to in silico modelling and design. Our Current libraries concentrate on highly selective hydrogenation transformations to generate novel 3D structures with high fsp3 characteristics. We have also developed special libraries for Central Nervous System (CNS) research. Scaffolds, Building Blocks and Fragment libraries also available.

Our customer-oriented vision means we place great emphasis on characteristic defined by our clients, resulting in more drug-like libraries.

We aspire for high-quality so our compounds can be formatted to meet the Lilly MedChem rules as well as the PAINS and QED filters and all undesired and reactive functionalities commonly avoided have been filtered out from ComInnex libraries!

Research Of New Synthesis Technologies

  • Flow Photoredox (collaboration with Tim Noel, TUE)
  • Metathesis (technology is already applied n DEL)
  • Deuteration
  • Cycloaddition

Innovation & Discovery

  • Assay, Target or indication specific libraries
  • Cycloadditions Enabled Libraries
  • Covalent inhibitors
  • Macrocyclic compounds