Guideline Towards the Synthesis of 3D Shaped N-Heterocycles
This guide provides useful information on performing hydrogenation of different N-heterocycles using flow chemistry principles. Optimized reaction conditions are listed towards the selective and high throughput synthesis of novel compounds featuring high sp3/sp2 ratio (fsp3), therefore favourable physico-chemical properties.
Continous Flow Photocatalytic Minisci Reaction Using N-(Acyloxy)Phthalimide Esters
we show how the photocatalytic Minisci reaction was employed in the synthesis of biologically active compounds to target the treatment of high mortality tumor diseases.
Furthermore, we describe our efforts towards the development of a continuous flow Minisci procedure. A novel, multiwavelength batch and flow photoreactor, the PhotoCube™ Pro – codeveloped by ComInnex and ThalesNano – was applied during some of these studies.